[81] Northwestern 14-38 Duke [21] 2023-09-16 19:30
Stadium: Brooks Field at Wallace Wade Stadium Round: 1
Home Manager: Mike Elko Away Manager: David Braun
Head to Head
| NCAAF | 2022/09/10 16:00 | Duke v Northwestern | L | 31-23 |
| NCAAF | 2021/09/18 20:00 | Northwestern v Duke | L | 23-30 |
| NCAAF | 2018/09/08 16:00 | Duke v Northwestern | L | 21-7 |
| NCAAF | 2017/09/09 16:00 | Northwestern v Duke | L | 17-41 |
| NCAAF | 2016/09/18 00:00 | Northwestern v Duke | W | 24-13 |
| NCAAF | 2015/09/19 16:30 | Duke v Northwestern | W | 10-19 |
| NCAAF | 2008/09/06 12:00 | Duke v Northwestern | W | 20-24 |
| NCAAF | 2007/09/15 12:00 | Northwestern v Duke | L | 14-20 |
Home History
| NCAAF | 2023/09/09 19:30 | UTEP v Northwestern | W | 7-38 |
| NCAAF | 2023/09/03 16:00 | Northwestern v Rutgers | L | 7-24 |
| NCAAF | 2022/11/26 20:30 | Illinois v Northwestern | L | 41-3 |
| NCAAF | 2022/11/19 17:00 | Northwestern v Purdue | L | 9-17 |
| NCAAF | 2022/11/12 20:30 | Northwestern v Minnesota | L | 3-31 |
| NCAAF | 2022/11/05 16:00 | Ohio State v Northwestern | L | 21-7 |
| NCAAF | 2022/10/29 19:30 | Northwestern v Iowa | L | 13-33 |
| NCAAF | 2022/10/22 19:30 | Northwestern v Maryland | L | 24-31 |
Away History
| NCAAF | 2023/09/09 22:00 | Lafayette v Duke | W | 7-42 |
| NCAAF | 2023/09/05 00:00 | Clemson v Duke | W | 7-28 |
| NCAAF - Bowl Games | 2022/12/28 19:00 | Central Florida v Duke | W | 13-30 |
| NCAAF | 2022/11/26 20:30 | Wake Forest v Duke | W | 31-34 |
| NCAAF | 2022/11/19 17:00 | Duke v Pittsburgh | L | 26-28 |
| NCAAF | 2022/11/12 17:00 | Virginia Tech v Duke | W | 7-24 |
| NCAAF | 2022/11/04 23:00 | Duke v Boston College | W | 38-31 |
| NCAAF | 2022/10/22 16:30 | Duke v Miami Florida | W | 45-21 |
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