Stadium: Bobcat Stadium Round: 1
Home Manager: Brent Vigen Away Manager: Gary Goff
| NCAAF | 2021/11/20 18:00 | Northwestern State v McNeese State | L | 24-20 |
| NCAAF | 2021/11/13 20:00 | McNeese State v Houston Christian | W | 44-3 |
| NCAAF | 2021/11/06 17:00 | Nicholls State v McNeese State | L | 24-14 |
| NCAAF | 2021/10/30 23:00 | McNeese State v SE Louisiana | L | 20-23 |
| NCAAF | 2021/10/23 17:00 | Incarnate Word v McNeese State | W | 20-28 |
| NCAAF | 2021/10/16 20:00 | McNeese State v Northwestern State | W | 35-17 |
| NCAAF | 2021/10/02 17:00 | SE Louisiana v McNeese State | L | 38-35 |
| NCAAF | 2021/09/25 16:00 | McNeese State v Incarnate Word | L | 0-31 |
| NCAAF | 2022/01/08 17:00 | Montana State v North Dakota State | L | 10-38 |
| NCAAF | 2021/12/18 19:00 | South Dakota State v Montana State | W | 17-31 |
| NCAAF | 2021/12/12 01:30 | Montana State v Sam Houston State | W | 42-19 |
| NCAAF | 2021/12/04 21:00 | Tennessee Martin v Montana State | W | 7-26 |
| NCAAF | 2021/11/20 19:00 | Montana State v Montana | L | 10-29 |
| NCAAF | 2021/11/13 20:00 | Idaho v Montana State | W | 13-20 |
| NCAAF | 2021/11/06 20:00 | Montana State v East Washington | W | 23-20 |
| NCAAF | 2021/10/23 19:00 | Idaho State v Montana State | W | 9-27 |