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Horseshoe Indianapolis (formerly Indiana Grand Racing & Casino and Indiana Live!) is a casino with a horse racing track in Shelbyville, Indiana owned and operated by Caesars Entertainment. It is the closest casino to Indianapolis. It offers gaming, restaurants, a gift shop and entertainment. The 233,000-square-foot (21,600 m2) facility has over 1,704 slot machines and live table games. It was built at a cost of more than $250 million.

Horseshoe Indianapolis' casino has hosted musicians such as The Buckinghams, Grand Funk Railroad, Duke Tumatoe of REO Speedwagon, Peter Noone of Herman's Hermits, The Lovin' Spoonful, The Box Tops, Paul Revere & the Raiders, The Fabulous Thunderbirds, The Kentucky Headhunters, Fuel, Marc Cohn, All-4-One, Color Me Badd, Ginuwine, Ludacris, and comedian Mike Epps.

The racetrack was previously known as Indiana Downs. The casino opened on March 13, 2009 as Indiana Live! Casino. It was renamed Indiana Grand Casino in June 2012, and rebranded as Indiana Grand Racing & Casino in February 2013. Centaur Gaming purchased the casino in February 2013. Caesars Entertainment acquired it in 2018. The Indiana Grand racetrack and casino complex were rebranded to Horseshoe Indianapolis in late January 2022, in line with other properties owned by Caesars.

Horseshoe Indianapolis offers live Thoroughbred and Quarter Horse racing from April through October. The track is affiliated with three OTB parlors around Indiana, in Clarksville, Indianapolis, and New Haven.

Horseshoe Indianapolis is the home of the Indiana Derby.